2-Chloro-1-(4-fluorobenzyl)benzimidazole

CAS: 84946-20-3

Ref. TR-C366290

Produktinformation

• Name: 2-Chloro-1-(4-fluorobenzyl)benzimidazole
• Synonyme: 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole, 1-(4'-Fluorobenzyl)-2-Chlorobenzimidazole, 1-(4-Fluorobenzyl)-2-Chloro-Benzimidazole, 1-(4-Fluorophenylmethyl)-2-Chlorobenzimidazole, 1H-Benzimidazole, 2-chloro-1-[(4-fluorophenyl)methyl]-, 2-Chloro-1-(4-Fluorobenzyl)-1H-Benzimidazole, 2-Chloro-1-[(4-Fluorophenyl)Methyl]-1H-Benzimidazole, 2-Chloro-1-[(4-fluorophenyl)methyl]-1H-1,3-benzodiazole, 2-Chloro-1-[(4-fluorophenyl)methyl]benzimidazole, 3-(4'-Fluorobenzy)-2-Chlorobenzimidazole, N-Methyl-N-(-Chloroethyl) Aniline
• CAS: 84946-20-3

Beschreibung

Applications A novel aldose reductase (ALR2) inhibitor. It is used for preparation of disubstituted benzimidazole derivative as anti-allergic agent (Mizolastine).
References Masson, E., et al.: Drugs, 39, 190 ( 1990), Lindstad, R., et al.: Eur. J. Biochem., 221, 847 (1994), Chien, D., et al.: J. Pharm. Sci., 86, 1180 (1997), Harrison, D., et al.: Biochemistry, 36, 16134 (1997), Da Settimo, F., et al.: J. Med. Chem., 44, 316 (2001),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 260.69
• Formel: C₁₄H₁₀ClFN₂
• Farbe/Form: Neat
• InChl: InChI=1S/C14H10ClFN2/c15-14-17-12-3-1-2-4-13(12)18(14)9-10-5-7-11(16)8-6-10/h1-8H,9H2
• InChI Key: InChIKey=PGXALMVNIRPELS-UHFFFAOYSA-N
• SMILES: Fc1ccc(Cn2c(Cl)nc3ccccc32)cc1