4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine

CAS: 479633-63-1

Ref. TR-C370130

Produktinformation

• Name: 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine
• Synonyme: 4-Chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidine, 4-Chloro-7-(4-methylphenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine
• Marke: TRC

Beschreibung

Applications 4-Chloro-7-tosyl-7H-pyrrolo[2,3-d]pyrimidine is a reagent in the synthesis of (+)-tofacitinib, a selective Janus kinase 3 inhibitor (JAK3) and an immunosuppressant drug.
References Liao, H., et al.: Tetrahedron: Asymmetry, 28, 105, (2017)

Chemische Eigenschaften

• Molekulargewicht: 307.76
• Formel: C₁₃H₁₀ClN₃O₂S
• Farbe/Form: Neat
• InChl: InChI=1S/C13H10ClN3O2S/c1-9-2-4-10(5-3-9)20(18,19)17-7-6-11-12(14)15-8-16-13(11)17/h2-8H,1H3
• InChI Key: InChIKey=BTOJSYRZQZOMOK-UHFFFAOYSA-N
• SMILES: Cc1ccc(S(=O)(=O)n2ccc3c(Cl)ncnc32)cc1