(R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-(4-trifluoromethoxybenzyl-d2-oxy)propyl-3,3-d2 Benzoate

Ref. TR-C375292

Produktinformation

• Name: (R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-(4-trifluoromethoxybenzyl-d2-oxy)propyl-3,3-d2 Benzoate
• Synonyme: [(2S)-3,3-dideuterio-2-hydroxy-3-(4-methylphenyl)sulfonyloxypropyl] benzoate

Beschreibung

Applications (R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-(4-trifluoromethoxybenzyl-d2-oxy)propyl-3,3-d2 Benzoate is an intermediate used in the synthesis of (S)-PA 824-d4 (P122502), which is a labelled novel anti-tuberculosis drug.
References Diacon, A.H. et al.: Antimicrob. Anents Chemother., 54, 3402 (2010); Dogra, M. et al.: Br. J. Pharmacol., 162, 226 (2010); Ginsberg, A.M. et al.: Antimicrob. Agents Chemother., 53, 3720 (2009);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 352.399
• Formel: C₁₇D₂H₁₆O₆S
• Farbe/Form: Neat
• InChl: InChI=1S/C17H18O6S/c1-13-7-9-16(10-8-13)24(20,21)23-12-15(18)11-22-17(19)14-5-3-2-4-6-14/h2-10,15,18H,11-12H2,1H3/t15-/m0/s1/i12D2
• InChI Key: InChIKey=XNGCEIYTHLBYGJ-KHHHJSQISA-N
• SMILES: [2H]C([2H])(OS(=O)(=O)c1ccc(C)cc1)[C@@H](O)COC(=O)c1ccccc1