Ciclesonide-d11 (Mixture of Diastereomers)

CAS: 204444-45-1

Ref. TR-C432692

Produktinformation

• Name: Ciclesonide-d11 (Mixture of Diastereomers)
• Synonyme: (11ß,16a)-16,17-[[(R/S)-(Cyclohexyl-d11)-methylene]bis(oxy)]-11-hydroxy-21-(2-methyl-1-oxopropoxy)-pregna-1,4-diene-3,20-dione, Alvesco-d11, Omnaris-d11, RPR 251526-d11

Beschreibung

Applications A labelled glucocorticoid microemulsion nasal preparation allergy inhibitor rhinitis.This compound is a mixture of diastereomers at the cyclohexyl acetal.
References Fukuoka, E., et al.: Chem. Pharm. Bull., 35, 2943 (1987), Schmitt, E., et al.: J. Pharm. Sci., 88, 291 (1999), Hancock, B., et al.: Pharm. Res., 17, 397 (2000), Hogan, S., et al.: Pharm. Res., 18, 112 (2001).

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 551.76
• Formel: C₃₂D₁₁H₃₃O₇
• Farbe/Form: Neat
• InChl: InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29?,30-,31-,32+/m0/s1/i5D2,6D2,7D2,8D2,9D2,19D
• InChI Key: InChIKey=LUKZNWIVRBCLON-UACKNMOTSA-N
• SMILES: [2H]C1([2H])C([2H])([2H])C([2H])([2H])C([2H])(C2O[C@@H]3C[C@H]4[C@@H]5CCC6=CC(=O)C=C[C@]6(C)[C@H]5[C@@H](O)C[C@]4(C)[C@]3(C(=O)COC(=O)C(C)C)O2)C([2H])([2H])C1([2H])[2H]