Cilastatin Ammonium Salt

CAS: 877674-82-3

Ref. TR-C441110

Produktinformation

• Name: Cilastatin Ammonium Salt
• Synonyme: 2-Heptenoic acid, 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, ammonium salt (1:1), (2Z)-, 2-Heptenoic acid, 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, monoammoniu
• CAS: 877674-82-3

Beschreibung

Applications Sodium salt of Cilastatin (C441100), which prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.
References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983); Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983); Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 375.484
• Formel: C₁₆H₂₆N₂O₅S•(HN)
• Farbe/Form: Neat
• InChl: /h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23), InChI=1S/C16H26N2O5S.H3N/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21, /t10-,11+, /m1./s1, 1H3/b12-6-
• InChI Key: InChIKey=PEHMSHKUJVYVPY-QBNHLFMHSA-N
• SMILES: CC1(C)C[C@@H]1C(=O)N/C(=C\CCCCSC[C@H](N)C(=O)O)C(=O)O.N