Cilostazol-d4

CAS: 1215541-47-1

Ref. TR-C441503

Produktinformation

• Name: Cilostazol-d4
• Synonyme: 6-[4-(1-Cyclohexyl-d4-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone, OPC-13013-d4, Pletal-d4

Beschreibung

Applications Cilostazol-d4 is the labeled analogue of Cilostazol (C441500), a potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998); Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999); Tsuchikane, E., et al.: Circulation, 100, 21 (1999)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 373.49
• Formel: C₂₀H₂₃D₄N₅O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26)/i6D2,7D2
• InChI Key: InChIKey=RRGUKTPIGVIEKM-KXGHAPEVSA-N
• SMILES: [2H]C1([2H])CCCC([2H])([2H])C1n1nnnc1CCCCOc1ccc2c(c1)CCC(=O)N2