Chloroquine N-Oxide

CAS: 68121-48-2

Ref. TR-C542620

Produktinformation

• Name: Chloroquine N-Oxide
• Synonyme: 4-[(7-chloroquinolin-4-yl)amino]-N,N-diethylpentan-1-amine oxide, 1,4-Pentanediamine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-, N1-oxide, Chloroquine N-oxide

Beschreibung

Applications Chloroquine N-oxide is a metabolite of Chloroquine (C379965), a standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labelling of MRP by quinoline-based photoactive drug IAAQ.
References Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983), Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998), Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 335.872
• Formel: C₁₈H₂₆ClN₃O
• Farbe/Form: Neat
• InChl: InChI=1S/C18H26ClN3O/c1-4-22(23,5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)
• InChI Key: InChIKey=HPVLZIVCPLRCAH-UHFFFAOYSA-N
• SMILES: CC[N+]([O-])(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12