Produktinformation
- EKB 785
- EKI 785
- WAY-EKI 785
- N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-butynamide
- 2-Butynamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
- CL 387785
Applications CL-387785 (EKI-785) is an irreversible and selective EGFR inhibitor showing activity against mutations of the receptor. Potential therapeutic against various type of cancer, including lung cancer.
References Chiu, H. et al.: Mol. Oncol., 6, 299 (2012); Straussman, R. et al.: Nature, 487, 500 (2012);