Cladribine

CAS: 4291-63-8

Ref. TR-C557500

Produktinformation

• Name: Cladribine
• Synonyme: Adenosine, 2-chloro-2'-deoxy-, 2-Chloro-2'-deoxyadenosine, (2R,3S,5R)-5-(6-Amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol, 2-CdA, 2-Chlorodeoxyadenosine, Biodribin, Cladarabine, CldAdo, Jk 6251, Leustat, Leustatin, NSC 105014, NSC 105014-F, RWJ 26251, 2-Chloro-9-(2-deoxy-beta-d-erythro-pentofuranosyl)-9H-purin-6-amine, 2-Chloro-2'-deoxy-beta-adenosine, 2-Chloro-6-amino-9-(2-deoxy-beta-D-erythro-pentofuranosyl)purine, 2-Chloro-2'-deoxy-β-adenosine, 2-Chloro-6-amino-9-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)purine, 2-Chloro-6-amino-9-(2-deoxy-β-D-erythro-pentofuranosyl)purine, Litak, Mavenclad, Nsc 105014, Nsc 105014-F, Rwj 26251, Vero-Cladribine, Adenosine, 2-chloro-2′-deoxy-

Beschreibung

Applications It is a substituted purine nucleoside with antileukemic activity.
References Seto, S., et al.: J. Clin. Invest., 75, 377 (1985), Piro, L.D., et al.: N. Engl. J. Med., 322, 1117 (1990);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 285.69
• Formel: C₁₀H₁₂ClN₅O₃
• Farbe/Form: White To Light Yellow
• InChl: InChI=1S/C10H12ClN5O3/c11-10-14-8(12)7-9(15-10)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,6+/m0/s1
• InChI Key: InChIKey=PTOAARAWEBMLNO-KVQBGUIXSA-N
• SMILES: Nc1nc(Cl)nc2c1ncn2[C@H]1C[C@H](O)[C@@H](CO)O1