Clarithromycin (9Z)-O-Methyloxime

CAS: 127252-80-6

Ref. TR-C559775

Produktinformation

• Name: Clarithromycin (9Z)-O-Methyloxime
• Synonyme: 6-O-Methylerythromycin A (Z)-9-(O-methyloxime), Oxacyclotetradecane, erythromycin deriv., Clarithromycin Imp. O (EP)

Beschreibung

Impurity Clarithromycin Impurity O EP
Stability Hygroscopic
Applications Clarithromycin (9Z)-O-Methyloxime is an impurity of Clarithromycin (C559750); a semi-synthetic macrolide antibiotic and derivative of Erythromycin (E650000).
References Morgan, D., et al.: J. Chromatogr., 502, 351 (1990); Benson, C., et al.: Eur. J. Clin. Microbiol., 6, 173 (1987); Boyanova, L., et al.: J. Med. Microb., 61, 85 (2012); Lin, Z., et al.: Toxicol. Sci., 126, 114 (2012)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 776.99
• Formel: C₃₉H₇₂N₂O₁₃
• Farbe/Form: Beige Solid
• InChl: InChI=1S/C39H72N2O13/c1-16-27-39(10,46)32(43)22(4)29(40-49-15)20(2)18-38(9,48-14)34(54-36-30(42)26(41(11)12)17-21(3)50-36)23(5)31(24(6)35(45)52-27)53-28-19-37(8,47-13)33(44)25(7)51-28/h20-28,30-34,36,42-44,46H,16-19H2,1-15H3/b40-29-/t20-,21-,22+,23+,24-,25+,26+,27-,28+,30-,31+,32-,33+,34-,36+,37-,38-,39-/m1/s1
• InChI Key: InChIKey=BZXVFUGKJGEBBE-RDLANEIQSA-N
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)/C(=N/OC)[C@H](C)[C@@H](O)[C@]1(C)O