CP-471474

CAS: 210755-45-6

Ref. TR-C781305

Produktinformation

• Name: CP-471474
• Synonyme: 2-[[4-(4-fluorophenoxy)phenyl]sulfonylamino]-N-hydroxy-2-methylpropanamide

Beschreibung

Applications A broad spectrum inhibitor of matrix metalloproteinases that attenuates early left ventricular dilation after experimental myocardial infarction in mice. Studies show that it also inhibits cigarette smoke-induced lung inflammation and the progression of emphysema in guinea pig models.
References Lindsey, M.L. et al.: Circulation, 105, 753 (2002); Rohde, L.E. et al.: Circulation, 99, 3063 (1999); Selman, M. et al.: Chest, 123, 1633 (2003);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 368.38
• Formel: C₁₆H₁₇FN₂O₅S
• Farbe/Form: Neat
• InChl: InChI=1S/C16H17FN2O5S/c1-16(2,15(20)18-21)19-25(22,23)14-9-7-13(8-10-14)24-12-5-3-11(17)4-6-12/h3-10,19,21H,1-2H3,(H,18,20)
• InChI Key: InChIKey=QCOQJYRPDUMCNP-UHFFFAOYSA-N
• SMILES: CC(C)(NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1)C(=O)NO