CX 546

CAS: 215923-54-9

Ref. TR-C858000

Produktinformation

• Name: CX 546
• Synonyme: 2,3-dihydro-1,4-benzodioxin-6-yl(piperidin-1-yl)methanone, (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone, 1-(1,4-Benzodioxan-6-ylcarbonyl)piperidine, 1-(2,3-Dihydro-1,4-benzodioxin-6-ylcarbonyl)piperidine, 1-(2,3-Dihydro-1,4-benzodioxine-6-carbonyl)piperidine, 2,3-Dihydro-1,4-Benzodioxin-6-Yl(Piperidin-1-Yl)Methanone, Bdp 17, Gr 87, Methanone, (2,3-dihydro-1,4-benzodioxin-6-yl)-1-piperidinyl-, Piperidine, 1-[(2,3-dihydro-1,4-benzodioxin-6-yl)carbonyl]-

Beschreibung

Applications It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors.
References Partin, K., et al.: J. Neurosci.,16, 6634 (1996), Vanover, K., et al.: Eur. J. Pharmacol., 332, 115 (1997), Moser, P., et al.: Brain Res. Rev., 33, 275 (2000), Kinney, G., et al.: J. Pharmacol. Exp. Ther., 306, 116 (2003),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 247.29
• Formel: C₁₄H₁₇NO₃
• Farbe/Form: Neat
• InChl: InChI=1S/C14H17NO3/c16-14(15-6-2-1-3-7-15)11-4-5-12-13(10-11)18-9-8-17-12/h4-5,10H,1-3,6-9H2
• InChI Key: InChIKey=LJUNPHMOGNFFOS-UHFFFAOYSA-N
• SMILES: O=C(c1ccc2c(c1)OCCO2)N1CCCCC1