2-​Chloro-​1-​[2-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyridin-​3-​yl]​-1-propanone

CAS: 960355-08-2

Ref. TR-C960355

Produktinformation

• Name: 2-​Chloro-​1-​[2-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyridin-​3-​yl]​-1-propanone

Beschreibung

Applications 2-​Chloro-​1-​[2-​(1-​methylethyl)​pyrazolo[1,​5-​a]​pyridin-​3-​yl]​-1-propanone is an intermediate in the synthesis of AV1013 (2-Amino-1-[2-(1-methylethyl) pyrazolo[1,5-a] pyridin-3-yl]-1-propanone hydrochloride) (A618170), which is a drug candidate for the treatment of neuropathic pain, addiction behavior and drug withdrwal symptoms.
References Kirk, W. J. et al.: U.S. Pat. Appl. Publ. US 20100324082 A1 20101223 (2010).

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 250.72
• Formel: C₁₃H₁₅ClN₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C13H15ClN2O/c1-8(2)12-11(13(17)9(3)14)10-6-4-5-7-16(10)15-12/h4-9H,1-3H3
• InChI Key: InChIKey=VWSIWZSTGUBASV-UHFFFAOYSA-N
• SMILES: CC(Cl)C(=O)c1c(C(C)C)nn2ccccc12