1-Cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester

CAS: 172602-83-4

Ref. TR-C988505

Produktinformation

• Name: 1-Cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
• Synonyme: 3-Quinolinecarboxylic acid, 1-cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-, ethyl ester, Ethyl 1-cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate

Beschreibung

Applications 1-Cyclopropyl-8-ethoxy-6,7-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is used in the preparation of alkoxyquinolone antibacterial agents. Also an impurity in the synthesis of Moxifloxacin (M745000), a fluorinated quinolone antibacterial.
References Sanchez, J. et al.: J. Med. Chem., 38, 4478 (1995); Woodcock, J.M., et al.: Antimicrob. Ag. Chemother., 41, 101 (1997), Stass, H., et al.: Antimicrob. Ag. Chemother., 42, 2060 (1998)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 337.32
• Formel: C₁₇H₁₇F₂NO₄
• Farbe/Form: White
• InChl: InChI=1S/C17H17F2NO4/c1-3-23-16-13(19)12(18)7-10-14(16)20(9-5-6-9)8-11(15(10)21)17(22)24-4-2/h7-9H,3-6H2,1-2H3
• InChI Key: InChIKey=HVSSSDATQQUFJP-UHFFFAOYSA-N
• SMILES: CCOC(=O)c1cn(C2CC2)c2c(OCC)c(F)c(F)cc2c1=O