2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester

CAS: 2177283-35-9

Ref. TR-C989505

Produktinformation

• Name: 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester
• Synonyme: Ethyl 5-Chloro-2-(cyclobut-2-en-1-yl)-3-(trifluoromethyl)-1H-indole-1-carboxylate, Efavirenz Impurity
• Marke: TRC
• Beschreibung: Applications 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic acid ethyl ester is synthesized from 5-chloro-2-oxindole (C375030), which is used in the preparation of novel GSK-3β inhibitors as anticancer agents.References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012)

Chemische Eigenschaften

• Molekulargewicht: 343.73
• Formel: C₁₆H₁₃ClF₃NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C16H13ClF3NO2/c1-2-23-15(22)21-12-7-6-10(17)8-11(12)13(16(18,19)20)14(21)9-4-3-5-9/h3-4,6-9H,2,5H2,1H3
• InChI Key: InChIKey=AHNLTYRZGAIMGF-UHFFFAOYSA-N
• SMILES: CCOC(=O)n1c(C2C=CC2)c(C(F)(F)F)c2cc(Cl)ccc21