Cytarabine

CAS: 147-94-4

Ref. TR-C998100

Produktinformation

• Name: Cytarabine
• Synonyme: 4-Amino-1-β-d-arabinofuranosylpyrimidin-2(1H)-one, 2(1H)-Pyrimidinone, 4-amino-1-β-D-arabinofuranosyl-, Cytosine, 1-β-D-arabinofuranosyl- (6CI,8CI), 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone, (Arabinofuranosyl)cytosine, 1-(Arabinofuranosyl)cytosine, 1-(β-D-Arabinofuranosyl)cytosine, 1-β-Arabinofuranosylcytosine, 1-β-D-Arabinosylcytosine, 4-Amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one, 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidine, Ac 1075, Alexan, Ara-C, Ara-cell, Arabinocytosine, Arabinoside C, Arabitin, Aracytidine, Aracytin, Aracytine, Arafcyt, CHX 3311, Citozar, Cyclocide, Cylocide, Cylocide N, Cytarabin, Cytarabinoside, Cytosar, Cytosar U, Cytosine arabinoside, Cytosine β-D-arabinofuranoside, Cytosine β-D-arabinoside, Cytosine-1-β-D-arabinofuranoside, Cytosine-1-β-arabinofuranoside, DepoCyt, DepoCyte, Erpalfa, Iretin, MK 8242, NSC 287459, NSC 63878, SCH 900242, Spongocytidine, Tarabine PFS, U 19920, U 19920A, Udicil
• Marke: TRC
• Beschreibung: Applications Cytarabine is used as an antineoplastic and antiviral. It is a selective inhibitor of DNA synthesis. Does not inhibit RNA synthesis.Cytarabine, or cytosine arabinoside, is a chemotherapy agent used mainly in the treatment of cancers of white blood cells such as acute myeloid leukemia (AML) and non-Hodgkin lymphoma. It is also known as Ara-C (Arabinofuranosyl Cytidine). It destroys cancer cells by interfering with DNA synthesis.References Donehower, R.C., et al.: Cancer Treat. Rep., 70, 1059 (1986)

Chemische Eigenschaften

• Molekulargewicht: 243.22
• Formel: C₉H₁₃N₃O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1
• InChI Key: InChIKey=UHDGCWIWMRVCDJ-CCXZUQQUSA-N
• SMILES: Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O)c(=O)n1