3-Desbenzoyl-3-hydroxybenzyl Nepafenac

CAS: 1246956-18-2

Ref. TR-D204105

Produktinformation

• Name: 3-Desbenzoyl-3-hydroxybenzyl Nepafenac
• Synonyme: 2-Amino-3-(hydroxyphenylmethyl)-benzeneacetamide, Nepafenac Impurity E, 2-(2-Amino-3-(hydroxy(phenyl)methyl)phenyl) Acetamide

Beschreibung

Applications 3-Desbenzoyl-3-hydroxybenzyl Nepafenac is an impurity of Nepafenac (N390080), which is a selective COX-2 inhibitor, non-steroidal anti-inflammatory drug (NSAID) with analgesic activity. Nepafenac is also prodrug of Amfenac (A576500).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Walsh, D.A., et al.: J. Med. Chem., 33, 2296 (1990); Gamache, D.A., et al.: Inflammation, 24, 357 (2000); Lindstrom, R., et al.: Curr. Med. Res. Opin., 22, 397 (2006); Runje, M., et al.: J Pharm Biomed Anal, 123, 42 (2016);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 256.3
• Formel: C₁₅H₁₆N₂O₂
• Farbe/Form: White to Off-White Solid
• InChl: InChI=1S/C15H16N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8,15,19H,9,17H2,(H2,16,18)
• InChI Key: InChIKey=LXWNZCRPDAGUHQ-UHFFFAOYSA-N
• SMILES: NC(=O)Cc1cccc(C(O)c2ccccc2)c1N