Decarboxy Cilastatin

Ref. TR-D215340

Produktinformation

• Name: Decarboxy Cilastatin
• Synonyme: (S,Z)-7-((2-Aminoethyl)thio)-2-(2,2-dimethylcyclopropanecarboxamido)hept-2-enoic Acid
• Marke: TRC
• Beschreibung: Stability HygroscopicApplications Decarboxy Cilastatin is an impurity in the synthesis of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),

Chemische Eigenschaften

• Molekulargewicht: 314.443
• Formel: C₁₅H₂₆N₂O₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C15H26N2O3S/c1-15(2)10-11(15)13(18)17-12(14(19)20)6-4-3-5-8-21-9-7-16/h6,11H,3-5,7-10,16H2,1-2H3,(H,17,18)(H,19,20)/b12-6-
• InChI Key: InChIKey=SKFGHLOODSUVCX-SDQBBNPISA-N
• SMILES: CC1(C)CC1C(=O)N/C(=C\CCCCSCCN)C(=O)O