Decarboxy Fexofenadine

CAS: 185066-37-9

Ref. TR-D220750

Produktinformation

• Name: Decarboxy Fexofenadine
• Synonyme: Fexofenadine Imp. C (EP), Fexofenadine USP Related Compound C, Fexofenadine USP RC C, (1RS)-4-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]-1-[4-(1-methylethyl)phenyl]butan-1-ol, 1-Piperidinebutanol, 4-(hydroxydiphenylmethyl)-alpha-[4-(1-methylethyl)phenyl]-, 4-(Hydroxydiphenylmethyl)-alpha-[4-(1-methylethyl)phenyl]-1-piperidinebutanol, Fexofenadine Related Compound C, Fexofenadine Hydrochloride Impurity C, Fexofenadine Impurity C,(1RS)-4-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]-1-[4-(1-methylethyl)phenyl]butan-1-ol, Fexofenadine Hydrochloride Imp. C (EP)

Beschreibung

Impurity Fexofenadine EP Impurity C
Applications Decarboxy Fexofenadine is a photodegradation product of Fexofenadine (F322490), the active metabolite of Terfenadine (T114500), a H1-histamine receptor antagonist.
References Holzer, M., et al.: Molec., 13, 1081 (2008); Breier, A.R., et al.: J. Pharma. Biomed. Anal., 46, 250 (2008); Pratt, E., et al.: Diabet Med., 18, 515 (2001); Mizutani, N., et al.: J. Pharmacol. Sci., 93, 437 (2003)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 457.65
• Formel: C₃₁H₃₉NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C31H39NO2/c1-24(2)25-15-17-26(18-16-25)30(33)14-9-21-32-22-19-29(20-23-32)31(34,27-10-5-3-6-11-27)28-12-7-4-8-13-28/h3-8,10-13,15-18,24,29-30,33-34H,9,14,19-23H2,1-2H3
• InChI Key: InChIKey=FZSQPQGERLSIOR-UHFFFAOYSA-N
• SMILES: CC(C)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1