5’-Deshydroxy-5’-methoxy Rotigotine

CAS: 1148154-91-9

Ref. TR-D221705

Produktinformation

• Name: 5’-Deshydroxy-5’-methoxy Rotigotine
• Synonyme: 2-Thiopheneethanamine, N-propyl-N-[(2S)-1,2,3,4-tetrahydro-5-methoxy-2-naphthalenyl]-, N-Propyl-N-[(2S)-1,2,3,4-tetrahydro-5-methoxy-2-naphthalenyl]-2-thiopheneethanamine, (2S)-5-Methoxy-N-propyl-N-[2-(thiophen-2-yl)ethyl]-1,2,3,4-tetrahydronaphthalen-2-amine, Methoxy Rotigotine

Beschreibung

Applications 5’-Deshydroxy-5’-methoxy Rotigotine is an impurity of Rotigotine (R700700). Rotigotine is a non-ergot dopamine agonist drug and is indicated for the treatment of Parkinson’s disease.
References Loschmann, P., et al.: Eur. J. Pharmacol., 166, 373 (1989), Edgar, D., et al.: J. Pharmacol. Exp. Ther., 283, 757 (1997), Ferreira, J., et al.: Lancet, 355, 1333 (2000), Arnulf, I., et al.: Neurology, 58, 1019 (2002), Wisor, J., et al.: Neuroscience, 132, 1027 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 329.50
• Formel: C₂₀H₂₇NOS
• Farbe/Form: Neat
• InChl: InChI=1S/C20H27NOS/c1-3-12-21(13-11-18-7-5-14-23-18)17-9-10-19-16(15-17)6-4-8-20(19)22-2/h4-8,14,17H,3,9-13,15H2,1-2H3/t17-/m0/s1
• InChI Key: InChIKey=AXOQYAWBBDSEMG-KRWDZBQOSA-N
• SMILES: CCCN(CCc1cccs1)[C@H]1CCc2c(cccc2OC)C1