4’-(7-Dechloroquinolinyl) Piperaquine

CAS: 4039-00-3

Ref. TR-D226595

Produktinformation

• Name: 4’-(7-Dechloroquinolinyl) Piperaquine
• Synonyme: 7-Chloro-4-[4-[3-(1-piperazinyl)propyl]-1-piperazinyl]-quinoline, Piperaquine Impurity B

Beschreibung

Applications 4’-(7-Dechloroquinolinyl) Piperaquine is an impurity of Piperaquine (P480050, tetraphosphate) which is a 4-aminoquinoline derivative used as an antimalarial agent. Piperaquine interferes with physiological function of the food vacuole membrane of the trophozoites leading to autophagocytosis of the parasites.
References Nguyen, T.M.T. et al.: Tap Chi Duoc Hoc, 57, 22 (2007); Song, J. et al.: Malaria J., 10, 231 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 373.923
• Formel: C₂₀H₂₈ClN₅
• Farbe/Form: Neat
• InChl: InChI=1S/C20H28ClN5/c21-17-2-3-18-19(16-17)23-5-4-20(18)26-14-12-25(13-15-26)9-1-8-24-10-6-22-7-11-24/h2-5,16,22H,1,6-15H2
• InChI Key: InChIKey=BBXXLROWFHWFQY-UHFFFAOYSA-N
• SMILES: CCCCc1c(C)nc(NCC)[nH]c1=O