De(cladinosyl) Clarithromycin

CAS: 118058-74-5

Ref. TR-D226750

Produktinformation

• Name: De(cladinosyl) Clarithromycin
• Synonyme: 3-O-Decladinosyl-6-O-methylerythromycin A, Erythromycin, 3-O-de(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-6-O-methyl-, De(cladinosyl)clarithromycin, 3-O-De(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)-6-O-methylerythromycin, Oxacyclotetradecane, erythromycin deriv., 5-O-Desosaminyl-6-O-methylerythronolide A

Beschreibung

Impurity Clarithromycin EP Impurity I
Applications De(cladinosyl) Clarithromycin (Clarithromycin EP Impurity I) is an impurity of Clarithromycin (C559750). De(cladinosyl) Clarithromycin showed significantly potent antibacterial activity against community acquired respiratory pathogens.
References Morimoto, S., et al.: J. Antibiot., 37, 187 (1984), Buxbaum, A., et al.: J. Antimicrob. Chemother., 52, 371 (2003), Westphal, J., et al.: Br. J. Clin. Pharmacol., 50, 285 (2000), Ma, Z., et al.: J. Med. Chem., 44, 4137 (2001),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 589.76
• Formel: C₃₀H₅₅NO₁₀
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C30H55NO10/c1-12-21-30(8,37)25(35)17(4)22(32)15(2)14-29(7,38-11)26(18(5)23(33)19(6)27(36)40-21)41-28-24(34)20(31(9)10)13-16(3)39-28/h15-21,23-26,28,33-35,37H,12-14H2,1-11H3/t15-,16-,17+,18+,19-,20+,21-,23+,24-,25-,26-,28+,29-,30-/m1/s1
• InChI Key: InChIKey=RKPWKVGMLBEXFA-UHFFFAOYSA-N
• SMILES: CC(=O)OCc1c[n+]([O-])c(C)c(C)c1Cl