∆9,11-Dehydro-17a-cyanomethyl Estradiol

CAS: 86153-38-0

Ref. TR-D229505

Produktinformation

• Name: ∆9,11-Dehydro-17a-cyanomethyl Estradiol
• Synonyme: 19-Norpregna-1,3,5(10),9(11)-tetraene-21-nitrile, 3,17-dihydroxy-, (17a)- (9CI), 17a-Cyanomethylestra-1,3,5(10),9(11)-tetraene-3,17ß-diol, STS 825, [3,17-Dihydroxyestra-1,3,5(10),9(11)-tetraen-17a-yl]acetonitrile, 9,11-Dehydro-17a-cyanomethylestradiol
• CAS: 86153-38-0

Beschreibung

Applications ∆9,11-Dehydro-17α-cyanomethyl estradiol is a metabolite of progestin dienogest (D441870), and is currently being investigated for progesterone-receptor binding, progestational, antiprogestational, estrogenic and antigonadotropic activities for the inhibition of fertility. It is also being considered a novel treatment for heavy menstrual bleeding.
References Oettel, M., et al.: Pharmazie, 41, 627 (1993); Kiley, J. & Shulman, L.: Int. J. Womens Health, 3, 281 (2011);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 309.40
• Formel: C₂₀H₂₃NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C20H23NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h3,5-6,12,17-18,22-23H,2,4,7-10H2,1H3/t17-,18+,19+,20-/m1/s1
• SMILES: C[C@]12CC=C3c4ccc(O)cc4CC[C@H]3[C@@H]1CC[C@@]2(O)CC#N