(5'α,10α)-1-Demethyl-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-2,3(2H,3H)-secoergotaman-3,3',6',18-tetrone

CAS: 81149-12-4

Ref. TR-D231050

Produktinformation

• Name: (5'α,10α)-1-Demethyl-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-2,3(2H,3H)-secoergotaman-3,3',6',18-tetrone
• Synonyme: 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, 2,3(2H,3H)-secoergotaman-3,3',6',18-tetrone deriv., Benzo[f]quinoline, 2,3(2H,3H)-secoergotaman-3,3',6',18-tetrone deriv. (2R,4aR,10bR)-7-Amino-1,2,3,4,4a,5,6,10b-octahydro-4-methyl-N-[(2R,5S,10aS,10bS)-octahydro-10b-hydroxy-2-methyl-3,6-dioxo-5-(phenylmethyl)-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-6-oxo-benzo[f]quinoline-2-carboxamide
• Marke: TRC
• Beschreibung: Stability Temperature SensitiveApplications (5'α,10α)-1-Demethyl-9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-2,3(2H,3H)-secoergotaman-3,3',6',18-tetrone is a derivative of dihydroergotamine (D449080), a ergot alkaloid used to treat migraines.References Stadler, P.A., et al.: Euro. J. Med. Chem., 16, 349 (1981)

Chemische Eigenschaften

• Molekulargewicht: 587.67
• Formel: C₃₂H₃₇N₅O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C32H37N5O6/c1-31(34-28(39)19-15-21-20-10-6-11-22(33)27(20)25(38)16-23(21)35(2)17-19)30(41)37-24(14-18-8-4-3-5-9-18)29(40)36-13-7-12-26(36)32(37,42)43-31/h3-6,8-11,19,21,23-24,26,42H,7,12-17,33H2,1-2H3,(H,34,39)/t19-,21-,23-,24+,26+,31-,32+/m1/s1