N-Demethyl Lincomycin Hydrochloride

CAS: 14600-41-0

Ref. TR-D231320

Produktinformation

• Name: N-Demethyl Lincomycin Hydrochloride
• Synonyme: D-erythro-a-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S,4R)-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride (9CI), D-erythro-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(4-propyl-2-pyrrolidinecarboxamido)-1-thio-, hydrochloride (7CI), D-erythro-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans-a- (8CI), D-erythro-a-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[(4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-, 4'-Propyl-N-demethyllincomycin hydrochloride, Methyl 6,8-dideoxy-6-[[[(2S,4R)-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-a-D-galacto-octopyranoside hydrochloride, Lincomycin D hydrochloride, N-Demethyllincomycin hydrochloride, N-Desmethyllincomycin hydrochloride

Beschreibung

Stability Hygroscopic
Applications N-Demethyl Lincomycin Hydrochloride is an impurity of Lincomycin (L466200), an antibiotic produced by Streptomyces lincolnensis. Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA. Inhibits bacterial protein synthesis. Antibacterial.
References Mason, D.J., et al.: Antimicrob. Agents Chemother., 555 (1962); Gray, et al.: Toxicol. Appl. Pharmacol., 6, 476 (1964); Muti, H.Y., et al.: Anal. Profiles Drug Subs. Excip., 23, 269 (1994)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 428.97
• Formel: C₁₇H₃₂N₂O₆S·ClH
• Farbe/Form: Neat
• InChl: InChI=1S/C17H32N2O6S.ClH/c1-4-5-9-6-10(18-7-9)16(24)19-11(8(2)20)15-13(22)12(21)14(23)17(25-15)26-3;/h8-15,17-18,20-23H,4-7H2,1-3H3,(H,19,24);1H/t8-,9-,10+,11-,12+,13-,14-,15-,17-;/m1./s1
• InChI Key: InChIKey=CHKUTFKCSCMSCE-CULBYEROSA-N
• SMILES: CCC[C@H]1CN[C@H](C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)C(O)C(O)[C@H]2O)C1.Cl