Demethylzeylasteral

CAS: 107316-88-1

Ref. TR-D231408

Produktinformation

• Name: Demethylzeylasteral
• Synonyme: (20a)-2,3-Dihydroxy-6,23-dioxo-D:A-friedo-24-noroleana-1,3,5(10),7-tetraen-29-oic Acid, (9ß,13a,14ß,20a)-2,3-Dihydroxy-9,13-dimethyl-6,23-dioxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic Acid, TZ 93, (9β,13α,14β,20α)-2,3-Dihydroxy-9,13-dimethyl-6,23-dioxo-24,25,26-trinoroleana-1,3,5(10),7-tetraen-29-oic acid, 24,25,26-Trinoroleana-1,3,5(10),7-tetraen-29-oic acid, 2,3-dihydroxy-9,13-dimethyl-6,23-dioxo-, (9β,13α,14β,20α)-, D:A-Friedo-24-noroleana-1,3,5(10),7-tetraen-29-oic acid, 2,3-dihydroxy-6,23-dioxo-, (20α)-

Beschreibung

Applications Demethylzeylasteral is a natural product as new inhibitor to block the Bcl-XL-Bid interaction. Also, it is an immunosuppressive monomer isolated from the root xylem of Tripterygium wilfordii. It exhibits inhibition towards the glucuronidation elimination reaction of SN-38.
References Xu, M., et al.: Anal. Chem., 88, 8050-8057 (2016); An, H., et al.: Cell Biochem. Biophys., 73, 673-679 (2015)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 480.59
• Formel: C₂₉H₃₆O₆
• Farbe/Form: Neat
• InChl: InChI=1S/C29H36O6/c1-25-6-7-26(2,24(34)35)14-21(25)29(5)11-9-27(3)17-12-19(32)23(33)16(15-30)22(17)18(31)13-20(27)28(29,4)10-8-25/h12-13,15,21,32-33H,6-11,14H2,1-5H3,(H,34,35)/t21-,25-,26-,27+,28-,29+/m1/s1
• InChI Key: InChIKey=ZDZSFWLPCFRASW-CPISFEQASA-N
• SMILES: C[C@@]12CC[C@]3(C)C4=CC(=O)c5c(cc(O)c(O)c5C=O)[C@]4(C)CC[C@@]3(C)[C@@H]1C[C@](C)(C(=O)O)CC2