2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate

CAS: 1173824-58-2

Ref. TR-D232785

Produktinformation

• Name: 2-Deoxy-2,2-difluoro-D-erythro-ribofuranose-3,5-dibenzoate
• Synonyme: [(2R,3R)-3-benzoyloxy-4,4-difluoro-5-hydroxy-tetrahydrofuran-2-yl]methyl benzoate, D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate, 2-Deoxy-2,2-difuoro-D-Ribofuranose-3,5-dibenzoate, -1-methane sulfonate, 2-Deoxy-2,2-difuoro-D-Ribofuranose-3,5-dibenzoate-1-methane sulfonate, α/β-2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate, 2-deoxy-2,2-difluoro-3,5-bis-O-(phenylcarbonyl)-D-erythro-pentofuranose, 2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoate, 2-Deoxy-2,2-difluoro-D-ribofuranose-3,5-dibenzoates(alpha isomer), 3,5-Dibenzoyl-DDFR, 2-Deoxy-2,2-difluoro-alpha-D-erythro-pentofuranose 3,5-dibenzoate

Beschreibung

Applications Gemcitabine intermediate.
References Balzarini, J., et al.: Biochem. Pharmacol., 1988, 37, 2847 (1988), Hertel, L., et al.: Cancer Res., 50, 4417 (1990), Marquez, V., et al.: J. Med. Chem., 33, 978 (1990),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 378.32
• Formel: C₁₉H₁₆F₂O₆
• Farbe/Form: Colourless To Brown
• InChl: InChI=1S/C19H16F2O6/c20-19(21)15(27-17(23)13-9-5-2-6-10-13)14(26-18(19)24)11-25-16(22)12-7-3-1-4-8-12/h1-10,14-15,18,24H,11H2/t14-,15-,18?/m1/s1
• InChI Key: InChIKey=PRZDMMRKPZAYHW-QOYAAKSSSA-N
• SMILES: O=C(OC[C@H]1OC(O)C(F)(F)[C@@H]1OC(=O)c1ccccc1)c1ccccc1