5’-Deoxy-5-fluorouridine

CAS: 3094-09-5

Ref. TR-D235725

Produktinformation

• Name: 5’-Deoxy-5-fluorouridine
• Synonyme: 5-Fluorodesoxyuridine, Doxifluridine, Capecitabine Imp. B (EP), Capecitabine Related Compound B (USP), Capecitabine USP Related Compound B, Capecitabine USP RC B,5-Fluoro-5'-deoxyuridine, 1-(5-Deoxy-beta-D-ribofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione, Capecitabine Related Compound B, Capecitabine Impurity B, (2Xi)-5'-Deoxy-5-Fluorouridine, 5'-Deoxy-5-fluorouridine, 5'-Dfur, 5-Fluoro-5'-deoxyuridine, 5′-dFUrd, Flutron, Fulturon, Furtulon, Ro 21-9738, Uridine, 5′-deoxy-5-fluoro-

Beschreibung

Impurity USP Capecitabine Related Compound B
Applications 5’-Deoxy-5-fluorouridine is a metabolite of the chemotherapeutic agent Capecitabine (C175650). 5’-Deoxy-5-fluorouridine is an antitumor agent efficient in tumors, cell lines or in fibroblasts tranformed by H-ras or trk oncogenes.
References Ingle, J., et al.: Cancer, 67, 886 (1991); Harvey, J., et al.: J. Clin. Oncol., 17, 1474 (1999); Asai-Sato, M., et al.: Int. J. Cancer, 115, 539 (2005); Rastelli, F., et al.: Tumori, 94, 370 (2008);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 246.19
• Formel: C₉H₁₁FN₂O₅
• Farbe/Form: Neat
• InChl: InChI=1S/C9H11FN2O5/c1-3-5(13)6(14)8(17-3)12-2-4(10)7(15)11-9(12)16/h2-3,5-6,8,13-14H,1H3,(H,11,15,16)/t3-,5-,6-,8-/m1/s1
• InChI Key: InChIKey=ZWAOHEXOSAUJHY-GPJNPLOBSA-N
• SMILES: C[C@H]1O[C@@H](n2cc(F)c(=O)[nH]c2=O)[C@@H](O)[C@H]1O