3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid

CAS: 153666-19-4

Ref. TR-D239500

Produktinformation

• Name: 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid
• Synonyme: (4S,5R,6R)-2,4,5-trihydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid, Ketodeoxynonulosonic acid (Kdn), (2S,4S,5R,6R)-2,4,5-trihydroxy-6-[(1S,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylate (non-preferred name), (2S,4S,5R,6S)-2,4,5-trihydroxy-6-[(1S,2R)-1,2,3-trihydroxypropyl]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)

Beschreibung

Stability Hygroscopic
Applications A naturally occuring deaminated sialic acid, exclusively located at the non-reducing end of the sialyl chains. KDN is a sialic acid derivative with potential for anticancer activity. KDN has also been seen to be in elevated levels in human prostate cancer cells.
References Nadano, D., et al.: J. Biol. Chem., 261, 11550 (1986); Tiralongo, J. et al.: Carb. Mod. Biocatal., 477 (2012); Yabu, M. et al.: Glycobiol., 23, 634 (2013);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 268.22
• Formel: C₉H₁₆O₉
• Farbe/Form: Neat
• InChl: InChI=1S/C9H16O9/c10-2-4(12)6(14)7-5(13)3(11)1-9(17,18-7)8(15)16/h3-7,10-14,17H,1-2H2,(H,15,16)/t3-,4+,5+,6+,7+,9?/m0/s1
• InChI Key: InChIKey=CLRLHXKNIYJWAW-YOQZMRDMSA-N
• SMILES: O=C(O)[C@]1(O)C[C@H](O)[C@@H](O)[C@H]([C@H](O)[C@H](O)CO)O1