Dermorphin Trifluoroacetic Acid Salt

CAS: 78331-26-7

Ref. TR-D281940

Produktinformation

• Name: Dermorphin Trifluoroacetic Acid Salt
• Synonyme: L-Tyrosyl-D-alanyl-L-phenylalanylglycyl-L-tyrosyl-L-prolyl-L-serinamide Trifluoroacetate, Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 TFA Salt
• Marke: TRC
• Beschreibung: Applications Dermorphin is a hepta-peptide and a natural opioid initially isolated from the skin of South American hylid frogs Phyllomedusinae. Dermorphin binds as an agonist with high potency and selectivity to mu-opioid receptors. Dermorphin is about 30-40 times more potent than Morphine.References Erspamer, V. et al.: Proc. Nat. Acad. Sci. U.S.A., 86, 5188 (1989); Negri, L. et al.: Hand. Biol. Act. Pep., 268 (2006); Broccardo, M. et al.: Br. J. Pharmacol., 73, 625 (1981)

Chemische Eigenschaften

• Molekulargewicht: 916.90
• Formel: C₄₀H₅₀N₈O₁₀•C₂HF₃O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C40H50N8O10.C2HF3O2/c1-23(44-37(55)29(41)18-25-9-13-27(50)14-10-25)36(54)46-30(19-24-6-3-2-4-7-24)38(56)43-21-34(52)45-31(20-26-11-15-28(51)16-12-26)40(58)48-17-5-8-33(48)39(57)47-32(22-49)35(42)53;3-2(4,5)1(6)7/h2-4,6-7,9-16,23,29-33,49-51H,5,8,17-22,41H2,1H3,(H2,42,53)(H,43,56)(H,44,55)(H,45,52)(H,46,54)(H,47,57);(H,6,7)/t23?,29-,30-,31-,32-,33-;/m0./s1