2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide

CAS: 199734-71-9

Ref. TR-D288235

Produktinformation

• Name: 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide
• Synonyme: (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-3-sulfonamide

Beschreibung

Applications 2-Desaminosulfonyl 3-Aminosulfonyl Dorzolamide is a useful synthetic compound. Also, it is derived from (4R,6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-ol 7,7-Dioxide (T344510), which is an analog of topically-active carbonic anhydrase inhibitor MK-507, commonly known Dorzolamide (D535100).
References Blacklock, T., et al.: J. Org. Chem., 58, 1672 (1993); Tempkin, O., et al.: Tetrahedron: Asym., 7, 2721 (1996)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 324.44
• Formel: C₁₀H₁₆N₂O₄S₃
• Farbe/Form: Off-White
• InChl: InChI=1S/C10H16N2O4S3/c1-3-12-7-4-6(2)18(13,14)10-9(7)8(5-17-10)19(11,15)16/h5-7,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,7-/m0/s1
• InChI Key: InChIKey=OYKFJBJRSHWGIS-BQBZGAKWSA-N
• SMILES: CCN[C@H]1C[C@H](C)S(=O)(=O)c2scc(S(N)(=O)=O)c21