Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem

CAS: 42399-49-5

Ref. TR-D288450

Produktinformation

• Name: Des[3-Acetyl-5-(2-dimethylamino)ethyl] Diltiazem
• Synonyme: Diltiazem Hydrochloride Imp. E (EP), Diltiazem Imp. E (EP), (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one, Diltiazem Hydrochloride Impurity E, Diltiazem Impurity E, (2S,3S)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, (2S,3S)-3-Hydroxy-2-(4-Methoxy-Phenyl)-2,3-Dihydro-5H-Benzo[B][1,4]Thiazepin-4-One, (2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one, (2S-Cis)-(+)-Dihydro-3-Oh-2-(4-Meo-Ph)-1 ,5-Benzothiazepin-4(5H)-One, 98%, 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-, (2S,3S)-, 1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-, (2S-cis)-, 5-Benzothiazepin-4(5H)-One,2,3-Dihydro-3-Hydroxy-2-(4-Methoxyphenyl)-(2S-C, Cis (+) Hydroxy Lactam, Cis-2,3-Dihydro-3-Hydroxy-2-(4-Methoxyphenyl)-1,5-Benzothiazepin-4(5H)-One, Hydroxy Lactam

Beschreibung

Applications A key intermediate for Diltiazem (D460620) synthesis.
References Nagao, T., et al.: Jpn. J. Pharmacol., 22, 1 (1972), Senuma, M., et al.: Chem. Pharm. Bull., 37, 3204 (1989), Kometani, T., et al.: J. Ferment. Bioeng., 80, 208 (1995),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 301.36
• Formel: C₁₆H₁₅NO₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C16H15NO3S/c1-20-11-8-6-10(7-9-11)15-14(18)16(19)17-12-4-2-3-5-13(12)21-15/h2-9,14-15,18H,1H3,(H,17,19)/t14-,15+/m1/s1
• InChI Key: InChIKey=LHBHZALHFIQJGJ-CABCVRRESA-N
• SMILES: COc1ccc([C@@H]2Sc3ccccc3NC(=O)[C@@H]2O)cc1