Desacetyl Diltiazem

CAS: 42399-40-6

Ref. TR-D288685

Produktinformation

• Name: Desacetyl Diltiazem
• Synonyme: (2S,3S)-5-[2-(Dimethylamino)-ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one, Diltiazem Hydrochloride Imp. F (EP), Desacetyldiltiazem, Diltiazem Hydrochloride Impurity F, Diltiazem Impurity F, (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one, (2S,3S)-5-[2-(Dimethylamino)ethyl]-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one, 1,5-Benzothiazepin-4(5H)-one, 5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-, (2S-cis)-, 1,5-benzothiazepin-4(5H)-one, 5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-, (2S,3S)-, 255-795-9, Deacetyl-d-diltiazem, Deacetyldiltiazem

Beschreibung

Impurity Diltiazem EP Impurity F
Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).
References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 372.48
• Formel: C₂₀H₂₄N₂O₃S
• Farbe/Form: Neat
• InChl: InChI=1S/C20H24N2O3S/c1-21(2)12-13-22-16-6-4-5-7-17(16)26-19(18(23)20(22)24)14-8-10-15(25-3)11-9-14/h4-11,18-19,23H,12-13H2,1-3H3/t18-,19+/m1/s1
• InChI Key: InChIKey=NZHUXMZTSSZXSB-MOPGFXCFSA-N
• SMILES: COc1ccc([C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2O)cc1