N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride

CAS: 111974-74-4

Ref. TR-D288740

Produktinformation

• Name: N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride
• Synonyme: Quetiapine Fumarate Imp. B (EP), Quetiapine Imp. B (EP), Quetiapine USP Related Compound B, Quetiapine USP RC B, 11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine Dihydrochloride, Quetiapine Fumarate Imp. B (EP) as Dihydrochloride, Quetiapine Related Compound B as Dihydrochloride, Quetiapine Fumarate Impurity B as Dihydrochloride, Quetiapine Impurity B as Dihydrochloride, 11-(1-Piperazinyl)-Dibenzo[B,F][1,4]Thiazepine Dihydrochloride, 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine,2HCl, 11-(Piperazin-1-Yl)Dibenzo[B,F][1,4]Thiazepine, 11-Piperazin-1-Yldibenzo[B,F][1,4]Thiazepine Dihydrochloride, 11-Piperazin-1-yl-dibenzo[b,f][1,4]thiazepine dihydrochloride, 11-Piperazine-Dibenzo[B,F][1,4]Thiazepine Hydrochloride, 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride, 11-Piperazynil-Dibenzo[B,F][1,4]Thiazepine Dihydrochloride, 11-piperazinyl-dibenzo[b,f][1,4]thiazepine 2HCl, Dbtp, DibenzoB,F1,4Thiazepine-11-Piperazine2Hcl, Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, dihydrochloride, Dibenzo[b,f][1,4]thiazepine, 11-(1-piperazinyl)-, hydrochloride (1:2), dibenzo[b,f][1,4]thiazepine-11-[10H]piperazine dihydrochloride

Beschreibung

Impurity Quetiapine EP Impurity B
Applications N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride (Quetiapine EP Impurity B) is a metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
References DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001), Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2004), Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2004), Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2006),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 368.32
• Formel: C₁₇H₁₇N₃SClH
• Farbe/Form: White
• InChl: InChI=1S/C17H17N3S.2ClH/c1-3-7-15-13(5-1)17(20-11-9-18-10-12-20)19-14-6-2-4-8-16(14)21-15;;/h1-8,18H,9-12H2;2*1H
• InChI Key: InChIKey=PZQCQHZDUIIKFU-UHFFFAOYSA-N
• SMILES: Cl.Cl.c1ccc2c(c1)N=C(N1CCNCC1)c1ccccc1S2