N-Ethyl Azilsartan Medoxomil

CAS: 1417576-01-2

Ref. TR-D289263

Produktinformation

• Name: N-Ethyl Azilsartan Medoxomil
• Synonyme: 2-Ethoxy-1-[[2'-(4-ethyl-4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylic Acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Ester
• Marke: TRC
• Beschreibung: Applications N-Ethyl Azilsartan Medoxomil is an impurity from the synthesis of Azilsartan Medoxomil (A926910). Azilsartan medoxomil is a long-acting angiotensin II receptor blocker (ARB) that is used to lower hypertension. When Azilsartan medoxomil enters the gastrointestinal tract, it is rapidly converted to its active form, Azilsartan (A926900).References Radl, S., et al.: Org. Process. Res. Dev., 17), 77-86 (2013); Baker, W. & White, W.: Pharmacotherapy, 45, 1506 (2011); Cushman, W., et al.: Hypertension, 60, 310 (2012); Lastra, G., et al.: Cardio. Med. 3, 154 (2013); Miura, S., et al.: Hypertens. Res., 36, 134 (2012); Rakugi, H., et al.: Hypertens. Res., 35, 552 (2012)

Chemische Eigenschaften

• Molekulargewicht: 596.587
• Formel: C₃₂H₂₈N₄O₈
• Farbe/Form: Neat
• InChl: InChI=1S/C32H28N4O8/c1-4-35-28(34-44-31(35)38)23-10-7-6-9-22(23)21-15-13-20(14-16-21)17-36-27-24(11-8-12-25(27)33-30(36)40-5-2)29(37)41-18-26-19(3)42-32(39)43-26/h6-16H,4-5,17-18H2,1-3H3
• InChI Key: InChIKey=MKIYPVLTVAXBIW-UHFFFAOYSA-N
• SMILES: CCOc1nc2cccc(C(=O)OCc3oc(=O)oc3C)c2n1Cc1ccc(-c2ccccc2-c2noc(=O)n2CC)cc1