2-Deschlorothien-3-yl Tioconazole Hydrochloride

CAS: 61709-33-9

Ref. TR-D289560

Produktinformation

• Name: 2-Deschlorothien-3-yl Tioconazole Hydrochloride
• Synonyme: Tioconazole USP Related Compound A, Tioconazole USP RC A,1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-(3-thienylmethoxy)ethyl]-, hydrochloride (1:1), 1H-Imidazole, 1-[2-(2,4-dichlorophenyl)-2-(3-thienylmethoxy)ethyl]-, monohydrochloride (9CI), Tioconazole Imp. A (EP), Tioconazole Related Compound A as Hydrochloride, Tioconazole Impurity A as Hydrochloride
• CAS: 61709-33-9

Beschreibung

Applications 2-Deschloro Tioconazole Hydrochloride is an analog of Tioconazole (T444680), an antifungal that is more active than Fluconazole (F421000) or Voriconazole (V760000) against Candida glabrata mutant strains. Antifungal (topical).
References Jevons, S., et al.: Antimicrob. Agents Chemother., 15, 597 (1979), Clayton, Y.M., et al.: Clin. Exp. Dermatol., 7, 543 (1982), Marriott, M.S., et al.: Dermatologica, 166, 1 (1983),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 389.73
• Formel: C₁₆H₁₅Cl₃N₂OS
• Farbe/Form: Neat
• InChl: /h1-7,10-11,16H,8-9H2, InChI=1S/C16H14Cl2N2OS.ClH/c17-13-1-2-14(15(18)7-13)16(8-20-5-4-19-11-20)21-9-12-3-6-22-10-12, 1H
• InChI Key: InChIKey=VWTMBCHKRFCFFM-CCZBSFLLSA-N
• SMILES: OC[C@H]1C(O)C(O)[C@@H](CO)N1C(c1ccccc1)c1ccccc1