N’-Desmethyl Azithromycin

CAS: 172617-84-4

Ref. TR-D291000

Produktinformation

• Name: N’-Desmethyl Azithromycin
• Synonyme: 3'-N-Demtyhelazithromycin, CP 64434, N'-(Desmethyl)azithromycin,1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(methylamino)-ß-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-, 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(methylamino)-ß-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4R*,5R*,8R*,10R*,11R*,12S*,13S*,14R*)]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-a-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(methylamino)-ß-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one

Beschreibung

Impurity Azithromycin EP Impurity I
Stability Hygroscopic
Applications N’-Desmethyl Azithromycin (Azithromycin EP Impurity I) is a metabolite of Azithromycin (A927000) as potential anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agent.
References Bright, G., et al.: J. Antibiot., 41, 1029 (1988), Goldman, R., et al.: Antimicrob. Agents Chemother., 34, 426 (1990), Gandhi, R., et al.: J. Pharm. Biomed. Anal., 23, 1073 (2000),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 734.96
• Formel: C₃₇H₇₀N₂O₁₂
• Farbe/Form: White To Off-White
• InChl: InChI=1S/C37H70N2O12/c1-14-26-37(10,45)30(41)23(6)39(12)18-19(2)16-35(8,44)32(51-34-28(40)25(38-11)15-20(3)47-34)21(4)29(22(5)33(43)49-26)50-27-17-36(9,46-13)31(42)24(7)48-27/h19-32,34,38,40-42,44-45H,14-18H2,1-13H3/t19-,20-,21+,22-,23-,24+,25+,26-,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
• InChI Key: InChIKey=FZYUKBLYECHAGN-HOQMJRDDSA-N
• SMILES: CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](NC)C2O)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O