Desmethyl Cariprazine

CAS: 839712-15-1

Ref. TR-D291368

Produktinformation

• Name: Desmethyl Cariprazine
• Synonyme: N-[trans-4-[2-[4-(2,3-Dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N'-methyl Urea

Beschreibung

Applications Desmethyl Cariprazine, is a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.
References Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 413.38
• Formel: C₂₀H₃₀Cl₂N₄O
• Farbe/Form: Neat
• InChl: InChI=1S/C20H30Cl2N4O/c1-23-20(27)24-16-7-5-15(6-8-16)9-10-25-11-13-26(14-12-25)18-4-2-3-17(21)19(18)22/h2-4,15-16H,5-14H2,1H3,(H2,23,24,27)/t15-,16-
• InChI Key: InChIKey=WMQLLTKSISGWHQ-WKILWMFISA-N
• SMILES: CNC(=O)N[C@H]1CC[C@H](CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1