N-Desmethyl Loperamide

CAS: 66164-07-6

Ref. TR-D291840

Produktinformation

• Name: N-Desmethyl Loperamide
• Synonyme: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N-methyl-2,2-diphenylbutanamide, Desmethylloperamide, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-, 4-(4-Chlorophenyl)-4-hydroxy-N-methyl-α,α-diphenyl-1-piperidinebutanamide, R 20905

Beschreibung

Applications A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rahman, A., et al.: Cancer Res., 54, 5543 (1994), Sai, Y., et al.: Xenobiotica, 30, 327 (2000), Eneroth, A., et al.: Eur. J. Pharm. Sci., 12, 205 (2001), Kim, K., et al.: Drug Metab. Dispos., 31, 1090 (2003), Kannan et al. Drug Metab. Dispos., 38, 917 (2010)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 463.01
• Formel: C₂₈H₃₁ClN₂O₂
• Farbe/Form: White To Light Beige
• InChl: InChI=1S/C28H31ClN2O2/c1-30-26(32)28(23-8-4-2-5-9-23,24-10-6-3-7-11-24)18-21-31-19-16-27(33,17-20-31)22-12-14-25(29)15-13-22/h2-15,33H,16-21H2,1H3,(H,30,32)
• InChI Key: InChIKey=ZMOPTLXEYOVARP-UHFFFAOYSA-N
• SMILES: CNC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1