N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture)

CAS: 152764-52-8

Ref. TR-D292042

Produktinformation

• Name: N-Desmethyl-4-hydroxy Tamoxifen β-D-Glucuronide (E/Z Mixture)
• Synonyme: 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl β-D-Glucopyranosiduronic Acid, (E/Z)-Endoxifen Glucuronide
• Marke: TRC
• Beschreibung: Stability HygroscopicApplications A novel active metabolite of the anti-cancer drug Tamoxifen (T006000).References Furr, B., et al.: Pharmacol. Ther., 25, 127 (1984), Leonessa, F., et al.: Cancer Res., 54, 441 (1994), Stearns, V., et al.: Lancet, 360, 1851 (2002), Rae, J., et al.: Pharmacogenetics, 13, 501 (2003), Zheng, Y., et al.: Drug Metab. Dispos., 35, 1942 (2007),

Chemische Eigenschaften

• Molekulargewicht: 549.61
• Formel: C₃₁H₃₅NO₈
• Farbe/Form: Neat
• InChl: InChI=1S/C31H35NO8/c1-3-24(19-7-5-4-6-8-19)25(20-9-13-22(14-10-20)38-18-17-32-2)21-11-15-23(16-12-21)39-31-28(35)26(33)27(34)29(40-31)30(36)37/h4-16,26-29,31-35H,3,17-18H2,1-2H3,(H,36,37)/t26-,27-,28+,29-,31+/m0/s1
• InChI Key: InChIKey=HSQYCNXRYHIGKV-QXBBUDDSSA-N
• SMILES: CCC(=C(c1ccc(OCCNC)cc1)c1ccc(O[C@@H]2O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]2O)cc1)c1ccccc1