3-Desmethyl 2-Methyl Meclizine Dihydrochloride Monohydrate

Ref. TR-D292260

Produktinformation

• Name: 3-Desmethyl 2-Methyl Meclizine Dihydrochloride Monohydrate
• Synonyme: 1-((4-Chlorophenyl)(phenyl)methyl)-4-(2-methylbenzyl)piperazine Dihydrochloride Monohydrate, USP Meclizine Related Compound B

Beschreibung

Stability Hygroscopic
Applications 3-Desmethyl 2-Methyl Meclizine is a related compound to Meclizine Dihydrochloride (M202600), a nicotinic receptor antagonist; orally active ganglionic blocker. Antihypertensive.
References Cohen, B., et al.: Arch. Neurol., 27, 129 (1972); Stone, C.A., et al.: J. Med. Pharm. Chem., 5, 665 (1962), Papke, R.L., et al.: J. Pharmacol. Exp. Ther., 297, 646 (2001), Young, J.M., et al.: Clin. Ther., 23, 532 (2001),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 481.88544
• Formel: C₂₅H₂₉Cl₃N₂•H₂O
• Farbe/Form: Neat
• InChl: InChI=1S/C25H27ClN2.2ClH.H2O/c1-20-7-5-6-10-23(20)19-27-15-17-28(18-16-27)25(21-8-3-2-4-9-21)22-11-13-24(26)14-12-22;;;/h2-14,25H,15-19H2,1H3;2*1H;1H2
• InChI Key: InChIKey=PPUMIWNBDJVOBX-UHFFFAOYSA-N
• SMILES: Cc1ccccc1CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1.O