N-Despropargyl N-(1-Chloroprop-1-ene) Rasagiline

CAS: 1175018-74-2

Ref. TR-D297640

Produktinformation

• Name: N-Despropargyl N-(1-Chloroprop-1-ene) Rasagiline
• Synonyme: (1R)-N-[(2Z)-3-Chloro-2-propen-1-yl]-2,3-dihydro-1H-inden-1-amine

Beschreibung

Stability Light Sensitive
Applications N-Despropargyl N-(1-Chloroprop-1-ene) Rasagiline is used in the preparation of Rasagiline mesylate and chloro derivative impurities. Also, a derivative compound of Rasagiline mesylate (R126000) that functions an irreversible MAO-B inhibitor and also as an antiparkinsonian agent.
References Sterling, J., et al.: U.S. (2009), US 7572834 B1 20090811; Rabey, J. M., et al.: Clin. Neuropharmacol., 23, 324 (2000), Glezer, S., et al.: Eur. J. Pharmacol., 472, 173 (2003), Youdim, M.B.H., et al.: Biochem. Pharmacol., 66, 1635 (2003), Chen, J .J., et al.: J. Clin. Pharmacol., 45, 878 (2005),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 207.7
• Formel: C₁₂H₁₄ClN
• Farbe/Form: Light Yellow To Light Brown
• InChl: InChI=1S/C12H14ClN/c13-8-3-9-14-12-7-6-10-4-1-2-5-11(10)12/h1-5,8,12,14H,6-7,9H2/b8-3-/t12-/m1/s1
• InChI Key: InChIKey=MLLXGVLJGYOTNZ-CPWLGJMPSA-N
• SMILES: Cl/C=C\CN[C@@H]1CCc2ccccc21