16a-Dexamethasone 9,11-Epoxide 21-Propionate

CAS: 494870-08-5

Ref. TR-D298865

Produktinformation

• Name: 16a-Dexamethasone 9,11-Epoxide 21-Propionate
• Synonyme: (9ß,11ß,16a)-9,11-Epoxy-17-hydroxy-16-methyl-21-(1-oxopropoxy)-pregna-1,4-diene-3,20-dione

Beschreibung

Applications Dexamethasone 9,11-Epoxide 21-Propionate is an impurity of Dexamethasone (D298800) which is a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 428.52
• Formel: C₂₅H₃₂O₆
• Farbe/Form: Off-White To Beige
• InChl: InChI=1S/C25H32O6/c1-5-21(28)30-13-19(27)24(29)14(2)10-18-17-7-6-15-11-16(26)8-9-22(15,3)25(17)20(31-25)12-23(18,24)4/h8-9,11,14,17-18,20,29H,5-7,10,12-13H2,1-4H3/t14-,17+,18+,20+,22+,23+,24+,25-/m1/s1
• InChI Key: InChIKey=VHNLZHWRYPLCSE-XYCXANQISA-N
• SMILES: CCC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]34O[C@H]4C[C@@]21C