Dexamethasone 11,21-diacetate

CAS: 3949-26-6

Ref. TR-D298925

Produktinformation

• Name: Dexamethasone 11,21-diacetate
• Synonyme: Pregna-1,4-diene-3,20-dione, 11,21-bis(acetyloxy)-9-fluoro-17-hydroxy-16-methyl-, (11ß,16a)- (9CI), Pregna-1,4-diene-3,20-dione, 9-fluoro-11ß,17,21-trihydroxy-16a-methyl-, 11,21-diacetate (7CI,8CI), 9-Fluoro-17-hydroxy-16a-methyl-3,20-dioxopregna-1,4-diene-11ß,21-diyl Diacetate, Dexamethasone Acetate Impurity I

Beschreibung

Stability Hygroscopic
Applications Dexamethasone 11,21-diacetate, is an impuriy of Dexamethasone (D298800), a glucocorticoid used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.
References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995); Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999); Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 476.53
• Formel: C₂₆H₃₃FO₇
• Farbe/Form: Light Brown Solid
• InChl: InChI=1S/C26H33FO7/c1-14-10-20-19-7-6-17-11-18(30)8-9-23(17,4)25(19,27)22(34-16(3)29)12-24(20,5)26(14,32)21(31)13-33-15(2)28/h8-9,11,14,19-20,22,32H,6-7,10,12-13H2,1-5H3/t14-,19+,20+,22+,23+,24+,25+,26+/m1/s1
• InChI Key: InChIKey=GTECTIGXIMGLJQ-CBPGRDKISA-N
• SMILES: CC(=O)OCC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@H]3CCC4=CC(=O)C=C[C@]4(C)[C@]3(F)[C@@H](OC(C)=O)C[C@]21C