Dehydroxy Vildagliptin

CAS: 274901-16-5

Ref. TR-D357360

Produktinformation

• Name: Dehydroxy Vildagliptin
• Synonyme: (2R)-1-[2-(1-adamantylamino)acetyl]pyrrolidine-2-carbonitrile, (-)-(2S)-1-[[(3-Hydroxytricyclo[3.3.1.1[3,7]]dec-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile, (2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carbonitrile, (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile, (2S)-1-[N-(3-hydroxytricyclo[3.3.1.1~3,7~]dec-1-yl)glycyl]pyrrolidine-2-carbonitrile, (3R)-3-amino-1-[6-(trifluoromethyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-2(1H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate (1:1), (S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile, 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)amino]acetyl]-, (2S)-, 2-Pyrrolidinecarbonitrile, 1-[[(3-hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)amino]acetyl]-, (2S)-, Dsp 7238, Galvus, Jalra, Laf 237, Nvp-Laf 237, Vidagliptin, Xiliarx, 2-Pyrrolidinecarbonitrile, 1-[[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-, Vildagliptin, 2-Pyrrolidinecarbonitrile, 1-[2-[(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-, (2S)-, (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile

Beschreibung

Applications Dehydroxy Vildagliptin is the impurity of Glyptins(V305000) which are class of oral anti-hyperglycemic agents that inhibit dipeptidyl peptidase 4 (DPP-4), which can act as a serine exopeptidase. Aside from their use in type 2 diabetes, gliptins have positive cardiovascular and anti-inflammtatory effects. Antidiabetic.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 287.4
• Formel: C₁₇H₂₅N₃O
• Farbe/Form: Neat
• InChl: InChI=1S/C17H25N3O/c18-10-15-2-1-3-20(15)16(21)11-19-17-7-12-4-13(8-17)6-14(5-12)9-17/h12-15,19H,1-9,11H2/t12-,13+,14-,15-,17?/m1/s1
• InChI Key: InChIKey=DMSVTURYSDBBDR-JSMXJDTGSA-N
• SMILES: N#C[C@H]1CCCN1C(=O)CNC12C[C@H]3C[C@@H](C1)C[C@@H](C2)C3