4-​(2,​3-​Dichlorophenyl)​-​1,​4-​dihydro-​2,​6-​dimethyl-​3-​pyridinecarboxylic acid Methyl Ester

CAS: 253597-20-5

Ref. TR-D396480

Produktinformation

• Name: 4-​(2,​3-​Dichlorophenyl)​-​1,​4-​dihydro-​2,​6-​dimethyl-​3-​pyridinecarboxylic acid Methyl Ester
• Synonyme: methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3-carboxylate
• CAS: 253597-20-5

Beschreibung

Applications 4-​(2,​3-​Dichlorophenyl)​-​1,​4-​dihydro-​2,​6-​dimethyl-​3-​pyridinecarboxylic acid Methyl Ester is an impurity of Clevidipine (C573700), a calcium channel blocker, used as an oral antihypertensive.
References Odenstedt, J., et al.: J. Cardiovas., Pharmacol., 44, 407 (2004), Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006), Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), Varon, J., et al.: Drugs, 68, 283 (2008)

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 312.191
• Formel: C₁₅H₁₅Cl₂NO₂
• Farbe/Form: Neat
• InChl: InChI=1S/C15H15Cl2NO2/c1-8-7-11(10-5-4-6-12(16)14(10)17)13(9(2)18-8)15(19)20-3/h4-7,11,18H,1-3H3
• InChI Key: InChIKey=XYZHDDQUXWJPQN-UHFFFAOYSA-N
• SMILES: COC(=O)C1=C(C)NC(C)=CC1c1cccc(Cl)c1Cl