2,7-Diamino-6-phenyl-4-pteridinol

CAS: 19375-89-4

Ref. TR-D416685

Produktinformation

• Name: 2,7-Diamino-6-phenyl-4-pteridinol
• Synonyme: 4(3H)-Pteridinone, 2,7-diamino-6-phenyl-, 4(1H)-Pteridinone, 2,7-diamino-6-phenyl- (9CI), 4-Pteridinol, 2,7-diamino-6-phenyl- (8CI), 2,7-Diamino-4-hydroxy-6-phenylpteridine, Triamterene Imp. B (EP), Triamterene RC B (USP), Triamterene Related Compound B, Triamterene Impurity B

Beschreibung

Impurity Triamterene EP Impurity B/ Triamterene USP Related Compound B
Applications 2,7-Diamino-6-phenyl-4-pteridinol has potential as a pteridine diuretic. Impurity in the synthesis of Triamterene (T767325), a weak diuretic with potassium sparing properties; blocks Na+ reuptake in the kidneys.
References Osdene, et al.: J. Med. Chem., 10, 431 (1967), Kapoor, V.K., et al.: Anal. Profiles Drug Subs. Excip., 23, 571 (1994); Weinstock, J. et al.: J. Med. Chem., 11, 573 (1968);

• Marke: TRC

Chemische Eigenschaften

• Molekulargewicht: 254.25
• Formel: C₁₂H₁₀N₆O
• Farbe/Form: Neat
• InChl: InChI=1S/C12H10N6O/c13-9-7(6-4-2-1-3-5-6)15-8-10(16-9)17-12(14)18-11(8)19/h1-5H,(H5,13,14,16,17,18,19)
• InChI Key: InChIKey=UDZYJMZMGMKNJZ-UHFFFAOYSA-N
• SMILES: Nc1nc2[nH]c(N)c(-c3ccccc3)nc-2c(=O)n1