(S)-(5S,6S,8S)-5,8-Dibenzyl-12,12-dimethyl-3,10-dioxo-1-(thiazol-5-yl)-2,11-dioxa-4,9-diazatridecan-6-yl 2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate

CAS: 566939-06-8

Ref. TR-D417120

Produktinformation

• Name: (S)-(5S,6S,8S)-5,8-Dibenzyl-12,12-dimethyl-3,10-dioxo-1-(thiazol-5-yl)-2,11-dioxa-4,9-diazatridecan-6-yl 2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate
• Marke: TRC
• Beschreibung: Applications (S)-(5S,6S,8S)-5,8-Dibenzyl-12,12-dimethyl-3,10-dioxo-1-(thiazol-5-yl)-2,11-dioxa-4,9-diazatridecan-6-yl 2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoate is an protected prodrug of Ritonavir (R535000), which is a selective HIV protease inhibitor.

Chemische Eigenschaften

• Molekulargewicht: 821.06
• Formel: C₄₂H₅₆N₆O₇S₂
• Farbe/Form: Neat
• InChl: InChI=1S/C42H56N6O7S2/c1-27(2)36(47-39(50)48(8)23-32-25-56-37(44-32)28(3)4)38(49)54-35(21-31(19-29-15-11-9-12-16-29)45-41(52)55-42(5,6)7)34(20-30-17-13-10-14-18-30)46-40(51)53-24-33-22-43-26-57-33/h9-18,22,25-28,31,34-36H,19-21,23-24H2,1-8H3,(H,45,52)(H,46,51)(H,47,50)/t31?,34-,35-,36-/m0/s1
• InChI Key: InChIKey=WYMQFSIDOUJQGN-FCHUYYIVSA-N
• SMILES: COC(=O)[C@H](OC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1)c1ccccc1Cl