2’,3’-Dideoxyinosine

CAS: 69655-05-6

Ref. TR-D440950

Produktinformation

• Name: 2’,3’-Dideoxyinosine
• Synonyme: Didanosine, 2',3'-dideoxyinosine, 9-(2,3-Dideoxy-β-d-glycero-pentofuranosyl)-1,9-dihydro-6H-purin-6-one
• Marke: TRC

Beschreibung

Applications 2’,3’-Dideoxyinosine is a purine analog (1) which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2).
References 1. Esplugues, J. et al.: AIDS. 2016 Jun 1;30(9):1341-51.2. Blas-Garcia, A. et al.: J. Antimicrob. Chemother. 2016 Apr;71(4):916-26

Chemische Eigenschaften

• Molekulargewicht: 236.23
• Formel: C₁₀H₁₂N₄O₃
• Farbe/Form: Neat
• InChl: InChI=1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1
• InChI Key: InChIKey=BXZVVICBKDXVGW-NKWVEPMBSA-N
• SMILES: OC[C@@H]1CC[C@H](n2cnc3c(O)ncnc32)O1