N-Didesmethyl Loperamide

CAS: 66164-06-5

Ref. TR-D441135

Produktinformation

• Name: N-Didesmethyl Loperamide
• Synonyme: 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylbutanamide
• Marke: TRC

Beschreibung

Applications A metabolite of Loperamide; a new and improved PET radiotracer for imaging P-gp function.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rahman, A., et al.: Cancer Res., 54, 5543 (1994), Sai, Y., et al.: Xenobiotica, 30, 327 (2000), Eneroth, A., et al.: Eur. J. Pharm. Sci., 12, 205 (2001), Kim, K., et al.: Drug Metab. Dispos., 31, 1090 (2003),

Chemische Eigenschaften

• Molekulargewicht: 448.98
• Formel: C₂₇H₂₉ClN₂O₂
• Farbe/Form: Neat
• InChl: InChI=1S/C27H29ClN2O2/c28-24-13-11-21(12-14-24)26(32)15-18-30(19-16-26)20-17-27(25(29)31,22-7-3-1-4-8-22)23-9-5-2-6-10-23/h1-14,32H,15-20H2,(H2,29,31)
• InChI Key: InChIKey=PXJHDOGGBLQFRX-UHFFFAOYSA-N
• SMILES: NC(=O)C(CCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1